Selfing, adaptation and background selection in finite populations
نویسندگان
چکیده
منابع مشابه
Selfing, adaptation and background selection in finite populations.
Classic deterministic genetic models of the evolution of selfing predict species should be either completely outcrossing or completely selfing. However, even species considered high selfers outcross to a small degree (e.g. Arabidopsis thaliana and Caenorhabditis elegans). This discrepancy between theory and data may exist because the classic models ignore the effects of drift interacting with s...
متن کاملBackground Selection in Partially Selfing Populations.
Self-fertilizing species often present lower levels of neutral polymorphism than their outcrossing relatives. Indeed, selfing automatically increases the rate of coalescence per generation, but also enhances the effects of background selection and genetic hitchhiking by reducing the efficiency of recombination. Approximations for the effect of background selection in partially selfing populatio...
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Predictions are made of the equilibrium genetic variances and responses in a metric trait under the joint effects of directional selection, mutation and linkage in a finite population. The "infinitesimal model" is analyzed as the limiting case of many mutants of very small effect, otherwise Monte Carlo simulation is used. If the effects of mutant genes on the trait are symmetrically distributed...
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Genomic traits such as codon usage and the lengths of noncoding sequences may be subject to stabilizing selection rather than purifying selection. Mutations affecting these traits are often biased in one direction. To investigate the potential role of stabilizing selection on genomic traits, the effects of mutational bias on the equilibrium value of a trait under stabilizing selection in a fini...
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We investigate the evolutionary dynamics of a finite population of RNA sequences replicating on a neutral network. Despite the lack of differential fitness between viable sequences, we observe typical properties of adaptive evolution, such as increase of mean fitness over time and punctuated-equilibrium transitions, after initial mutation-selection balance has been reached. We find that a produ...
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ژورنال
عنوان ژورنال: Journal of Evolutionary Biology
سال: 2014
ISSN: 1010-061X
DOI: 10.1111/jeb.12343